A study from ETH Zurich reveals that fat cells retain a 'memory' of obesity due to epigenetic changes, making weight maintenance difficult after loss. This phenomenon, known as the 'yo-yo' effect, is linked to impaired fat cell functioning. Research on humans and mice shows that fat cells behave as if they are still obese even after weight loss, emphasizing the importance of avoiding obesity initially. Teljes cikk (Euronews.com)